Introduction to feed additives that can replace antibiotics

In recent years, people have developed antibiotic substitutes such as feed enzyme preparations, feed microbial preparations, acidifiers, antibacterial peptides, oligosaccharides, allicin, Chinese herbal medicines and trace elements of organic metals. These green feed additives have been used by people. Favor. - fgu China Feed Industry Information Network - based on feed, serving livestock

Enzyme preparation fgu China feed industry information network - based on feed, service animal husbandry

Since the establishment of the first enzyme preparation plant in Wuxi in 1965, after more than 30 years of efforts, China's enzyme preparation products have been increasing and the quality has been continuously improved. At present, α-amylase, β-amylase, protease and lipase have been developed. Hundreds of products such as cellulase, pectinase, β-glucanase, mannosidase, and phytase. At present, the most commonly used enzyme preparation feed additives are divided into two categories: one is mainly based on degrading polysaccharides and biomacromolecules, mainly including proteases, lipases, amylases, saccharification enzymes, cellulases, xylanases, Mannanase. Its main function is to destroy the plant cell wall (the plant cell wall is connected by a protein, fat, and polysaccharide green bond to a network structure), so that the cell contents are fully released. The other type is mainly based on anti-nutritional factors such as phytic acid, β-glucan and pectin, including phytase, β-glucanase and pectinase. It can degrade the pectin component of cell wall xylan and intercellular substance and improve the utilization rate of feed. Carbohydrate enzymes include digestion of non-starch polysaccharides, proteases that increase the utilization of soy or other plant proteins; lipases promote the breakdown and utilization of fats, and phytase increases the digestion and absorption of phosphorus and other mineral elements. For broiler feeds prepared with 30% soybean meal and 60% corn, the theoretical value of mannan is 0.42%, which will reduce feed utilization by 7.5%. With mannanase, feed conversion efficiency can be increased by 7.7% and cost savings by 10%. Fgu China Feed Industry Information Network - based on feed, serving animal husbandry

Feed microbial preparation fgu China feed industry information network - based on feed, service animal husbandry

Probiotics are direct-fed microbials (DFM) or live bacteria preparations or bactericides that can be directly fed to animals. In 1989, the US Food and Drug Administration (FDA) and the Feed Control Officer Association published 40 safe and effective microbial strains. Fgu China Feed Industry Information Network - based on feed, serving animal husbandry

(1) Lactic acid bacteria preparation Lactobacillus acidophilus, Lactobacillus brevis and Streptococcus faecalis. Lactic acid bacteria can survive under micro-aerobic or anaerobic conditions under acidic conditions of pH 3.0-4.5. It can break down sugars to produce lactic acid, and Acidoline can effectively inhibit the growth of Escherichia coli and Salmonella, but it is not heat-resistant and dies at 65-75 °C. Fgu China Feed Industry Information Network - based on feed, serving animal husbandry

The Bacillus preparations include Bacillus licheniformis, Bacillus subtilis, Bacillus cereus, and Oriental bacillus, etc., belonging to Bacillus aeruginosa, which are sporadicly present in the microflora of the intestine of the animal. When applied, the live bacterial preparation in the dormant state of the fungus is prepared or mixed with the lactic acid bacteria. The product has many advantages: acid resistance, salt tolerance, high temperature resistance (100 ° C) and resistance to extrusion, stability; can produce protease, lipase, amylase. Fgu China Feed Industry Information Network - based on feed, serving animal husbandry

(3) Fungi and live yeast preparations There are currently two commonly used products, Aspergillus oryzae and Saccharomyces cerevisiae cultures, which are preparations including fungi and cultures thereof, and are mostly used in ruminants. Its main feature is aerobic, hi-growth in the polysaccharide, acid environment; and its body is rich in protein and a variety of B vitamins, but not heat. Fgu China Feed Industry Information Network - based on feed, serving animal husbandry

The main role of probiotics: to maintain the micro-ecological balance in the intestine, probiotics can produce hydrolase, fermentation enzymes and respiratory enzymes, anti-pollution of probiotics, immunomodulation of probiotics. Fgu China Feed Industry Information Network - based on feed, serving animal husbandry

Acidifier fgu China feed industry information network - based on feed, service animal husbandry

Acidifiers can be classified into organic acids and inorganic acids. Organic acids are mainly citric acid, fumaric acid, etc.; the commonly used inorganic acid is phosphoric acid. Animal stomach is an acidic environment, and most of the bacteria are acid-producing bacteria and acid-resistant bacteria. The ability of young animals to secrete gastric acid is weak, and the foreign bacteria are easy to survive and multiply. The use of an acidifier can increase the acidity of the gastric juice, promote the proliferation of acid-fast bacteria such as lactic acid bacteria, and maintain the status of dominant bacteria in the stomach, while the foreign bacteria such as Escherichia coli can not adapt to the acidic environment, and can not be colonized by the "squeezing" of lactic acid bacteria. Survival can therefore reduce the incidence of pathological diarrhea in animals. The acidifier also helps the body adjust the immune system response and enhance the disease resistance of the animal. Fgu China Feed Industry Information Network - based on feed, serving animal husbandry

Organic acids can improve the digestion process (especially for monogastric animals, the effect of poultry is not obvious, poultry effect is not significant; in the digestion process, protein, carbohydrate digestion, need to continuously consume H +, the use of organic acids can reduce intestinal pH; The replication of microbial DNA inhibits the colonization of undesirable microorganisms at the front end of the digestive tract. The addition of organic and inorganic acids to the feed can be used as a method to protect the health of animals without the use of antibiotics. The acidifier directly stimulates the taste bud cells of the mouth and makes saliva. Increased secretion, promotes appetite, improves protein digestibility and protein deposition, is conducive to the absorption of trace elements, and enhances the ability to resist disease. Adding organic acids can increase the acidity of immature digestive tracts of young animals and activate some important digestive enzymes. It is beneficial to the digestion of nutrients. Acidified diet can inhibit or prevent the colonization and reproduction of E. coli or other harmful microorganisms in the intestine, prevent the occurrence of intestinal diseases, and improve the anti-stress ability of animals.

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